by Sarah Apr 24,2025
Bringing a super-sized canine back from extinction after 12,500 years might sound like a plot from a blockbuster movie filled with special effects, but it's now a reality. The world is home to three dire wolves, residing in a secret location in the US, thanks to the efforts of the biotech company Colossal Biosciences.

“I could not be more proud of the team. This massive milestone is the first of many coming examples demonstrating that our end-to-end de-extinction technology stack works,” stated Ben Lamm, CEO of Colossal Biosciences.
“Our team took DNA from a 13,000-year-old tooth and a 72,000-year-old skull and created healthy dire wolf puppies. It was once said, ‘any sufficiently advanced technology is indistinguishable from magic.’ Today, our team gets to unveil some of the magic they are working on and its broader impact on conservation.”

However, the ambitions of Colossal Biosciences extend beyond social media buzz and exotic pets. The company aims to apply its discoveries to conserve current species for future generations.
“The de-extinction of the dire wolf and an end-to-end system for de-extinction is transformative and heralds an entirely new era of human stewardship of life,” remarked Dr. Christopher Mason, a scientific advisor and member of the board of observers for Colossal.
“The same technologies that created the dire wolf can directly help save a variety of other endangered animals as well. This is an extraordinary technological leap in genetic engineering efforts for both science and for conservation as well as preservation of life, and a wonderful example of the power of biotechnology to protect species, both extant and extinct.”
Regarding the welfare of these dire wolves, Colossal Biosciences has collaborated with the American Humane Society and the USDA to ensure their 2,000+ acre preserve meets the highest standards, with a dedicated team providing round-the-clock care for these remarkable creatures.
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